Molecular biology of bacterial bioluminescence

Molecular Biology of Bacterial Viruses

The subject matter of this Ciba symposium departs from the usual specialized, esoteric topics of these meetings. Bringing together such noted scientists as Sir Julian Huxley, Joshua Lederberg, Albert Szent-Gy6rgi, and J. B. S. Haldane, this conference discusses the future of mankind as seen through the eyes of people actively engaged in biological research. These men don the philosopher's hat a...

Oscillation in Bacterial Bioluminescence

Molecular Imaging Using Bioluminescence

Recent progress in the development of non-invasive imaging technologies continues to strengthen the role of molecular imaging in biological research. Small animal imaging with bioluminescence has been validated recently in a variety of research models and have been shown to provide continuous quantitative monitoring of the location(s), magnitude, and time-variation of gene delivery and/or expre...

Biochemistry and genetics of bacterial bioluminescence.

Bacterial light production involves enzymes-luciferase, fatty acid reductase, and flavin reductase-and substrates-reduced flavin mononucleotide and long-chain fatty aldehyde-that are specific to bioluminescence in bacteria. The bacterial genes coding for these enzymes, luxA and luxB for the subunits of luciferase; luxC, luxD, and luxE for the components of the fatty acid reductase; and luxG for...

Molecular biology applied to the laboratory diagnosis of bacterial endophthalmitis.

Bacterial endophthalmitis is a serious but uncommon intraocular infection which frequently results in vision loss. Early diagnosis and appropriate therapy are associated with better visual outcome. Conventional microbiological methods are currently used for microbiological characterization of eyes with suspected endophthalmitis. However, the sensitivity of bacterial detection from aqueous and v...